This lecture video represents excerpt 2 of session 1 "DNA Structure and Classic Experiments" from "Molecular Biology" unit in "Fundamentals of Biology" course that Massachusetts Institute of Technology OpenCourseWare has published online to be available to the public.
Fundamentals of Biology focuses on the basic principles of biochemistry, molecular biology, genetics, and recombinant DNA. These principles are necessary to understanding the basic mechanisms of life and anchor the biological knowledge that is required to understand many of the challenges in everyday life, from human health and disease to loss of biodiversity and environmental quality.
This course has been designed for independent study. It consists of four units, one for each topic. The topics are biochemistry, molecular biology, genetics and recombinant DNA. Every unit contains multiple sessions.
Molecular Biology Unit, Session 1: DNA Structure and Classic Experiments
Instructor: Eric Lander
This session will explain early experiments in Molecular Biology. Outlined are classic experiments by Avery, Griffith, Hershey, and Chase that demonstrated DNA was the hereditary material, background on Chargaff, Watson, Crick, and Franklin and how their discoveries contributed to the discovery of the structure of DNA, and details regarding how the semi-conservative model of DNA replication was shown by Meselson and Stahl.