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Cancer
Combination Thereby Increase Survival of Patients with Sarcoma
Adding a novel monoclonal antibody therapy to traditional chemotherapy increased median survival by nearly a year in patients with advanced sarcoma, a lethal soft-tissue cancer. Findings from a multic... Read More
Researchers Identify Genetic Regions Important for Immune Response Against Cancer
Scientists at the Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified over 100 new genetic regions that affect the immune response to cancer. The findings, published in Cancer Imm... Read More
Researchers Identify Transcription Factors That Drive Formation of T Cells
The fates of various cells in our bodies—whether they become skin or another type of tissue, for example—are controlled by genetic switches. In a new study, Caltech scientists investigate ... Read More
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Genetics
Researchers Identify Genetic Mutations Responsible for a Rare Aortic Disease
A new finding by clinicians and geneticists may solve a medical mystery that one family has faced for the last 15 years and help identify the cause of a rare aortic disease in other patients as well. ... Read More
Researcher Discover a New Gene Responsible for Hydrophobic Coating of Insects
An international team of scientists led by University of Hawai'i at Mānoa researcher Joanne Yew may have discovered a new and effective way to control insect pests that are a threat to agricultur... Read More
Researchers Reveal How GA Sequence Repeats in X Chromosome Allowed Male Survival to Become Possible
Without a way to equalize the gene expression of the two sex chromosomes—males have XY and females have XX—gender could never have evolved. Scientists are still discovering many details on... Read More
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Stem Cells
Researchers Discover a New Micro-RNA Controls Self Renewal Process of Stem Cells
International stem cell scientists, co-led in Canada by Dr. John Dick and in the Netherlands by Dr. Gerald de Haan, have discovered the switch to harness the power of cord blood and potentially increa... Read More
Researcher Identify Chemical and Biological Signals Necessary to Quickly Produce 12 Cells Types from Stem Cells
Researchers at the Stanford University School of Medicine have mapped out the sets of biological and chemical signals necessary to quickly and efficiently direct human embryonic stem cells to become p... Read More
"Fillings that heal your teeth – how regenerative medicine could change your visit to the dentist"
Nottingham University and Wyss institute at Harvard University have developed a new material that can be inserted into teeth to repair and regenerate dentin - the hard, bone-like tissue that makes up ... Read More
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Diseases
Researchers Proves Efficacy of Exercise on Patients With Knee Damage
Exercise therapy is as effective as surgery for middle aged patients with a common type of knee injury known as meniscal tear (damage to the rubbery discs that cushion the knee joint), finds a study i... Read More
Diabetes Worsens Prognosis of ACS Patients
For patients with acute coronary syndromes (ACS), diabetes confers a worse prognosis, according to a study published in the Aug. 1 issue of The American Journal of Cardiology. Raffaele Piccolo, M.D., ... Read More
Scientists Reveal Why HIV-Infected Immune System Stay Active After Inhibiting Proliferation of the Virus
Investigators from the National Institutes of Health have discovered that cells from HIV-infected people whose virus is suppressed with treatment harbor defective HIV DNA that can nevertheless be tran... Read More
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Biochemistry
Researchers Reveal Mechanism by Which Plants Produce a Whole Set of Medicinal Compounds
Scientists at the John Innes Centre have discovered a key "twist" in a Rubik's cube-like plant puzzle, which could pave the way to new, or more effective pharmaceuticals. Several member... Read More
Researchers Develop a New Faster Method to Model Protein - Protein Interactions
Protein-protein interactions (PPIs) are the basis of cellular functions, and when these processes are compromised diseases such as cancer emerge. For years scientists have tried with mixed success to ... Read More
Researchers Explain Cardiovascular Side Effects of an Anti-Cancer Drug
A receptor protein that is the target of the breast cancer drug trastuzumab (Herceptin) is needed for proper heart blood-vessel development, reported researchers from the Perelman School of Medicine a... Read More
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Biotechnology
Researchers Study Unusual Mechanism of Action of an Anti-HIV Drug
A new type of HIV drug currently being tested works in an unusual way, scientists in the Molecular Medicine Partnership Unit, a collaboration between EMBL and Heidelberg University Hospital, have foun... Read More
Researcher Develop a New Technique to Treat Diseases Caused by a Mutation in a Bicistronic Gene
Neuroscientists at the University of Chicago studying a unique gene that expresses two proteins, one that is necessary for life and another, that when mutated causes a neurodegenerative disease called... Read More
Increasing Autophagy Decrease Lung Damage Induced by Hyperoxia
By triggering a process called autophagy—in which cells literally engulf their own insides —researchers from Drexel University and Yale University were able to decrease lung injury in mice... Read More
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Cell
Cellular Recycling Mechanisms Converge Inside One Organelle
Autophagy (literally "eating of self") is one of the most important process by which cells renew themselves and eliminate components no longer functional. In short, they recycle. The curren... Read More
Researchers Discover Additional Wall Surrounds Chloroplasts in Moss
Researchers of Kumamoto University in Japan have succeeded in the world's first visualization of a peptidoglycan 'wall' present in the chloroplasts of bryophytes (moss plants). Until now, ... Read More
Researcher Study Effects of Dietary Restriction on Longevity
Dietary restriction, or limited food intake without malnutrition, has beneficial effects on longevity in many species, including humans. A new study from the Sanford Burnham Prebys Medical Discovery I... Read More
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Technology
Saliva DNA Preservation Devices Used in "Detection of Novel Integrons in the Metagenome of Human Saliva"
Integrons are commonly found in bacterial genomes, especially in most Gram-negative bacteria. They are involved in the dissemination and differential expression of genes in the bacterial popula... Read More
New technique Developed to Deliver Chemotherapeutics to Brain Tumors
Great discoveries do come in small packages. Few know that better than Ann-Marie Broome, Ph.D., who feels nanotechnology holds the future of medicine with its ability to deliver powerful drugs in tiny... Read More
Camouflaged Trojan Horses Engineered to Specifically Target Inflammation
Nanosized Trojan horses created from a patient's own immune cells have successfully treated inflammation by overcoming the body's complex defense mechanisms, perhaps leading to broader applica... Read More
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Featured
New Diagnostic Tool Differentiates Aggressive DCIS Tumors from Non-aggressive Ones
When a woman is diagnosed with the earliest stage of breast cancer, how aggressive should her treatment be? Will the non-invasive cancer become invasive? Or is it a slow-growing variety that will like... Read More
Kataegis in Cancers Associated with Better Prognosis
Kataegis is a recently discovered phenomenon in which multiple mutations cluster in a few hotspots in a genome. The anomaly was previously found in some cancers, but it has been unclear what role kata... Read More
Modifying CAR T Cell Therapy to Target Autoimmune Disease
In a study with potentially major implications for the future treatment of autoimmunity and related conditions, scientists from the Perelman School of Medicine at the University of Pennsylvania have f... Read More
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General
Researchers Discover That Liver - Not the Spleen is the Major Site of Red Blood Cells Recycling
What happens when red blood cells become damaged or reach the end of their normal life span, and how is the iron required for carrying oxygen recycled? A new study led by Massachusetts General Hospita... Read More
Researchers Warns of Harmful Side Effects of Antioxidants
The lay press and thousands of nutritional products warn of oxygen radicals or oxidative stress and suggest taking so-called antioxidants to prevent or cure disease. Professor Pietro Ghezzi at the Bri... Read More
Scientists Reveal Why Artificial Sweeteners Increase Food Intake
Studies in both animals and humans have suggested that consuming artificial sweeteners can make you feel hungry and actually eat more. A comprehensive new study co-led by the University of Sydney has ... Read More
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Diabetes
Researchers Discover a New Protein Impairs Insulin Signaling
Medication can help trigger the enzyme that kick starts insulin production in the body, but the drugs don't always work for those who are obese or diabetic, and most need to regulate their glucose... Read More
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Immunology
Researchers Identify a Gene Implicated in Poor Immune Response Against Fungal Infection
Fungal infections pose a major threat to hospital patients and have proven difficult to combat, but scientists have unlocked evidence that could lead to more effective treatment. Researchers at The O... Read More
Genetics Impart Resistance Against Flu Virus Infections in Certain Bird Species
The genes of some chickens make them almost completely resistant to a serious strain of bird flu, new research has revealed. The findings, which are published in the journal Scientific Reports, show ... Read More
Researchers Identify Immune Cells That Guide Immune Response Against Cancer
Using advanced imaging technology that allowed them to spy on interactions among cells in the lymph nodes of living mice, a research team led by UCSF scientists has identified a cell that is a key pla... Read More
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Alzheimer's Disease
Researchers Reveal a Mechanism by Which Alzheimer Disease Spread Through Brain Regions
A toxic Alzheimer's protein can spread through the brain—jumping from one neuron to another—via the extracellular space that surrounds the brain's neurons, suggests new research fr... Read More
Researchers Develop Imaging Technique to Help Studying Amyloid Beta Plaques in Patients with Alzheimer
Rockefeller University researchers have used a recently-developed imaging technique that makes tissue transparent to visualize brain tissue from deceased patients with Alzheimer's disease, exposin... Read More
Functional Connectivity Patterns in Brain Can Be used as Biomarkers to Diagnose Alzheimer Disease
Researchers from Centre for Biomedical Technology (CTB) at Universidad Politécnica de Madrid (UPM) have shown that the abnormal pattern of functional connectivity in patients with mild cognitiv... Read More
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Neurodegenerative Diseases
Researchers Develop a New Imaging Technique to Quantify Functional Brain Synapsis
A Yale-led team of researchers developed a new approach to scanning the brain for changes in synapses that are associated with common brain disorders. The technique may provide insights into the diagn... Read More
Researchers Develop a New Drug That Treats Huntington Disease by Two Separate Mechanisms
A major, multi-institutional study based at Massachusetts General Hospital (MGH) has identified a promising treatment strategy for Huntington's disease (HD). In their report receiving online publi... Read More
A New Drug Protects From Neural Cell Death After Mild Traumatic Brain Injury
Whether at school, in car accidents, on the sports field or the battlefield, mild traumatic brain injury (mTBI) is a common part of our lives. It is especially frequent among children, athletes, and t... Read More
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