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Cancer
Researchers Discover Efficacy of a Known Drug in Treating Relapsed Blood Cancers Patients
For many patients with advanced blood cancers, a stem-cell transplant can drive the disease into remission. However, about one-third of these patients experience a relapse and face a very poor prognos... Read More
Researchers Proves Efficacy of a Group of Compounds in Killing Resistant Cancer Cells
Newly discovered molecules can kill multidrug resistant cancer cells by blocking cells' defenses against cancer drugs, according to a new study published in Bioorganic & Medicinal Chemistry Le... Read More
Researchers Discover a New Mechanism Imparts Drug Resistance to Certain Cancers
A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 ... Read More
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Genetics
Researchers Explains Epigenetic Mechanism That Turn off Genes After Being Active
Every time you play a game of basketball, make a cup of coffee or flick on a light switch, you are turning on genes in your brain. These same genes typically are turned off when the activity ceases - ... Read More
Genetics is Not the Only Cause of Familial Diseases
Family history of disease may be as much the result of shared lifestyle and surroundings as inherited genes, research has shown. Factors that are common to the family environment - such as shared liv... Read More
Researchers Reveal Why Tendon Injuries are Hard to Heal
With the Rio Olympics just weeks away, many are wondering how Jamaican sprinter Usain Bolt will perform. Bolt is the fastest runner ever timed, but he's also been nursing a tendon injury—the... Read More
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Stem Cells
Researchers Discover a New Micro-RNA Controls Self Renewal Process of Stem Cells
International stem cell scientists, co-led in Canada by Dr. John Dick and in the Netherlands by Dr. Gerald de Haan, have discovered the switch to harness the power of cord blood and potentially increa... Read More
Researcher Identify Chemical and Biological Signals Necessary to Quickly Produce 12 Cells Types from Stem Cells
Researchers at the Stanford University School of Medicine have mapped out the sets of biological and chemical signals necessary to quickly and efficiently direct human embryonic stem cells to become p... Read More
"Fillings that heal your teeth – how regenerative medicine could change your visit to the dentist"
Nottingham University and Wyss institute at Harvard University have developed a new material that can be inserted into teeth to repair and regenerate dentin - the hard, bone-like tissue that makes up ... Read More
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Diseases
Researchers Links Type II Diabetes to Changes in Gut Bacteria
Currently, scientists think the major contributors to insulin resistance are excess weight and physical inactivity, yet ground-breaking new research by an EU funded European-Chinese team of investigat... Read More
DNA Modulating Drugs Have Anti-inflammatory Effects in Cystic Fibrosis Lung Infections
Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage. Several recent studies have sug... Read More
Researchers Links Antibiotics Usage to Behavioral Changes in People With Mental Disorders
In research using patient medical records, investigators from Johns Hopkins and Sheppard Pratt Health System report that people with serious mental disorders who were hospitalized for mania were more ... Read More
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Biochemistry
Researchers Explain Cardiovascular Side Effects of an Anti-Cancer Drug
A receptor protein that is the target of the breast cancer drug trastuzumab (Herceptin) is needed for proper heart blood-vessel development, reported researchers from the Perelman School of Medicine a... Read More
Researchers Discover a New Gene That Controls Angiogenensis
In a study conducted by Duke-NUS Medical School (Duke-NUS) and the National Heart Centre Singapore (NHCS), researchers discovered a new gene that controls blood vessel formation. This work presents a ... Read More
Researchers Identify a New RNA Type that Controls Gene Methylation Process
The creation of memories in the brain involves addition or removal of methyl groups at precise spots on chromosomal DNA. But what controls the careful targeting of these neuronal DNA methylation dynam... Read More
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Biotechnology
Researchers Study Unusual Mechanism of Action of an Anti-HIV Drug
A new type of HIV drug currently being tested works in an unusual way, scientists in the Molecular Medicine Partnership Unit, a collaboration between EMBL and Heidelberg University Hospital, have foun... Read More
Researcher Develop a New Technique to Treat Diseases Caused by a Mutation in a Bicistronic Gene
Neuroscientists at the University of Chicago studying a unique gene that expresses two proteins, one that is necessary for life and another, that when mutated causes a neurodegenerative disease called... Read More
Increasing Autophagy Decrease Lung Damage Induced by Hyperoxia
By triggering a process called autophagy—in which cells literally engulf their own insides —researchers from Drexel University and Yale University were able to decrease lung injury in mice... Read More
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Cell
Researcher Distinguish Between Two Dopamine Neurons in the Brain
Two Northwestern University neuroscientists have identified the neurochemical signal likely missing in Parkinson's disease by being the first to discover two distinctly different kinds of neurons ... Read More
Scientists Reveal Anti-Aging Effects of Pomegranate
Are pomegranates really the superfood we've been led to believe will counteract the aging process? Up to now, scientific proof has been fairly weak. And some controversial marketing tactics have l... Read More
Researcher Identify a Protein in Drosophila That Resembles Characteristics of Intermediate Filament Proteins in Humans
Providing structural support and protection against such conditions as blistering, cataracts and dementia, intermediate filament proteins (IFs) reside in every cell in the human body. In insects, howe... Read More
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Technology
Saliva DNA Preservation Devices Used in "Detection of Novel Integrons in the Metagenome of Human Saliva"
Integrons are commonly found in bacterial genomes, especially in most Gram-negative bacteria. They are involved in the dissemination and differential expression of genes in the bacterial popula... Read More
New technique Developed to Deliver Chemotherapeutics to Brain Tumors
Great discoveries do come in small packages. Few know that better than Ann-Marie Broome, Ph.D., who feels nanotechnology holds the future of medicine with its ability to deliver powerful drugs in tiny... Read More
Camouflaged Trojan Horses Engineered to Specifically Target Inflammation
Nanosized Trojan horses created from a patient's own immune cells have successfully treated inflammation by overcoming the body's complex defense mechanisms, perhaps leading to broader applica... Read More
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Featured
New Diagnostic Tool Differentiates Aggressive DCIS Tumors from Non-aggressive Ones
When a woman is diagnosed with the earliest stage of breast cancer, how aggressive should her treatment be? Will the non-invasive cancer become invasive? Or is it a slow-growing variety that will like... Read More
Kataegis in Cancers Associated with Better Prognosis
Kataegis is a recently discovered phenomenon in which multiple mutations cluster in a few hotspots in a genome. The anomaly was previously found in some cancers, but it has been unclear what role kata... Read More
Modifying CAR T Cell Therapy to Target Autoimmune Disease
In a study with potentially major implications for the future treatment of autoimmunity and related conditions, scientists from the Perelman School of Medicine at the University of Pennsylvania have f... Read More
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General
Researchers Warns of Harmful Side Effects of Antioxidants
The lay press and thousands of nutritional products warn of oxygen radicals or oxidative stress and suggest taking so-called antioxidants to prevent or cure disease. Professor Pietro Ghezzi at the Bri... Read More
Scientists Reveal Why Artificial Sweeteners Increase Food Intake
Studies in both animals and humans have suggested that consuming artificial sweeteners can make you feel hungry and actually eat more. A comprehensive new study co-led by the University of Sydney has ... Read More
Researchers Identify a New Enzyme Crucial for Photosynthesis in Environments with Poor Light
Identification of a gene needed to expand light harvesting in photosynthesis into the far-red-light spectrum provides clues to the development of oxygen-producing photosynthesis, an evolutionary advan... Read More
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Diabetes
Researchers Discover a New Protein Impairs Insulin Signaling
Medication can help trigger the enzyme that kick starts insulin production in the body, but the drugs don't always work for those who are obese or diabetic, and most need to regulate their glucose... Read More
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Immunology
Immune System may Affects Our Social Behavior
School of Medicine have determined that the immune system directly affects - and even controls - creatures' social behavior, such as their desire to interact with others. So could immune system pr... Read More
Reactive Oxygen Molecules Block Immune System’s Responses Against Pathogens
Reactive oxygen species (ROS) such as peroxides and superoxides are important signalling molecules in an organism's regulation of metabolism and inflammation. Accumulation of ROS have been linked ... Read More
New Blood Test Discriminates Between Viral and Bacterial Infections
Researchers at the Stanford University School of Medicine have made an important breakthrough in their ongoing efforts to develop a diagnostic test that can tell health-care providers whether a patien... Read More
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Alzheimer's Disease
Functional Connectivity Patterns in Brain Can Be used as Biomarkers to Diagnose Alzheimer Disease
Researchers from Centre for Biomedical Technology (CTB) at Universidad Politécnica de Madrid (UPM) have shown that the abnormal pattern of functional connectivity in patients with mild cognitiv... Read More
A New Study Identify the First Sign of Alzheimer Disease
Scientists at the Montreal Neurological Institute and Hospital have used a powerful tool to better understand the progression of late-onset Alzheimer's disease (LOAD), identifying its first physio... Read More
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Neurodegenerative Diseases
A New Drug Protects From Neural Cell Death After Mild Traumatic Brain Injury
Whether at school, in car accidents, on the sports field or the battlefield, mild traumatic brain injury (mTBI) is a common part of our lives. It is especially frequent among children, athletes, and t... Read More
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